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Invitrogen
Phospho-RAD17 (Ser646) Polyclonal Antibody
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Phospho-RAD17 (Ser646) Antibody (PA5-34970) in ICC/IF
Immunofluorescent analysis of Phospho-RAD17 pSer646 showing staining in the nucleus of HCT116 cells. HCT116 cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a Phospho-RAD17 pSer646 polyclonal antibody (Product # PA5-34970) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-34970
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide contains a sequence corresponding to a region within amino acids 592 and 681 of Rad17 (phospho Ser646)
偶联物
形式
Liquid
浓度
1.61 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA5-34970 targets Phospho-RAD17 pSer646 in WB applications and shows reactivity with Human samples.
The PA5-34970 immunogen is synthetic peptide contains a sequence corresponding to a region within amino acids 592 and 681 of Rad17 (phospho Ser646).
靶标信息
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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