Invitrogen

Phospho-RAD9 (Ser272) Polyclonal Antibody

产品信息

PA5-64490

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:1,000	-

产品规格
种属反应	Human
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	A synthesized peptide derived from human RAD9 (Phospho-Ser272) 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	1 mg/mL
纯化类型	Affinity chromatography
保存液	PBS, pH 7.4, with 50% glycerol
内含物	0.02% sodium azide
保存条件	-20°C
RRID	AB_2664528

产品详细信息

Phospho-RAD9 (Ser272) Polyclonal Antibody detects endogenous levels of RAD9 only when phosphorylated at Ser272.

靶标信息

RAD9 is a component of the 9-1-1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesions upon damage by the RAD17-replication factor C clamp loader complex. RAD9 acts as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Cell cycle checkpoint control protein RAD9A; DNA repair exonuclease rad9 homolog A; hRAD9; RAD9 homolog A

基因别名: RAD9; RAD9A

UniProt ID: (Human) Q99638

Entrez Gene ID: (Human) 5883

分子生物学功能: exodeoxyribonuclease

功能

DNA replication checkpoint DNA damage checkpoint DNA replication DNA repair cellular response to DNA damage stimulus intra-S DNA damage checkpoint cellular response to ionizing radiation nucleic acid phosphodiester bond hydrolysis regulation of signal transduction by p53 class mediator positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

参与通路

protein binding 3'-5' exonuclease activity exodeoxyribonuclease III activity SH3 domain binding enzyme binding protein kinase binding histone deacetylase binding

Phospho-RAD9 (Ser272) Polyclonal Antibody

产品信息

PA5-64490

免疫印迹 (WB)

种属反应

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

RRID

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

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