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Invitrogen
Phospho-Rb (Thr373) Polyclonal Antibody
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产品信息
PA5-64767
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human Retinoblastoma (Phospho-Thr373)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Phospho-Rb (Thr373) Polyclonal Antibody detects endogenous levels of Rb only when phosphorylated at Thr373.
靶标信息
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
