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产品信息
PA5-64719
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human STMN2 (Phospho-Ser73) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2662679 |
产品详细信息
Phospho-STMN2 (Ser73) Polyclonal Antibody detects endogenous levels of STMN2 only when phosphorylated at Ser73.
靶标信息
STMN2, also known as SCG-10, is a neuronal growth-associated protein that shares significant amino acid sequence similarity with the phosphoprotein stathmin. STMN2 may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neuron-specific growth-associated protein; neuronal growth-associated protein (silencer element); Protein SCG10; SGC10; Stathmin-2; stathmin-like 2; superior cervical ganglia, neural specific 10; Superior cervical ganglion-10 protein; superiorcervical ganglia, neural specific 10
基因别名: AI159727; SCG10; SCGN10; Stmb2; STMN2
UniProt ID: (Human) Q93045, (Rat) P21818, (Mouse) P55821
Entrez Gene ID: (Human) 11075, (Rat) 84510, (Mouse) 20257
negative regulation of microtubule depolymerization
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of microtubule polymerization
positive regulation of microtubule depolymerization
cellular response to nerve growth factor stimulus
microtubule depolymerization
neuron projection development
regulation of cytoskeleton organization
regulation of microtubule polymerization or depolymerization
