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产品信息
PA5-64854
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human STYK1/NOK (Phospho-Tyr327) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2663669 |
产品详细信息
Phospho-STYK1 (Tyr327) Polyclonal Antibody detects endogenous levels of STYK1 only when phosphorylated at Tyr327.
靶标信息
STYK1, a probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. It is widely expressed; highly expressed in brain, placenta and prostate. STYK1 is expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp761P1010; mNOK; NOK kinase; Novel oncogene with kinase domain; Protein PK-unique; Serine/threonine/tyrosine kinase 1; Tyrosine-protein kinase STYK1
基因别名: 9130025L13; AI326477; NOK; STYK1; SuRTK106
UniProt ID: (Human) Q6J9G0, (Mouse) Q6J9G1
Entrez Gene ID: (Human) 55359, (Mouse) 243659
分子生物学功能:
transmembrane signal receptor
