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Product Details
PA5-17846
产品规格
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding serine 9 of human synapsin I
Conjugate
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
RRID
AB_10980023
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Brain protein 4.1; synapsin 1; Synapsin I; Synapsin-1; truncated synapsin 1-S
Gene Aliases: Syn-1; SYN1; Syn1-S; SYN1a; SYN1b; SYNI
UniProt ID: (Human) P17600, (Rat) P09951, (Mouse) O88935
Entrez Gene ID: (Human) 6853, (Rat) 24949, (Mouse) 20964
Molecular Function:
membrane trafficking regulatory protein
Performance Guarantee
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