7TM Antibodies

Phospho-Thyrotropin-Releasing Hormone Receptor 1 (Ser360) Polyclonal Antibody

Phospho-Thyrotropin-Releasing Hormone Receptor 1 (Ser360) Antibody in Western Blot (WB)

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Phospho-Thyrotropin-Releasing Hormone Receptor 1 (Ser360) Antibody (7TM0363A) in WB

Agonist-induced Serine360 phosphorylation of the TRH1-Receptor. Upper panel, HEK293 cells stably expressing the TRH1-Receptor (TRH1) were either not exposed or exposed to 1 µM of specific TRH1 Agonist Taltirelin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS360-TRH1 antibody (7TM0363A) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an phosphorylation-independ... View More

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产品信息

7TM0363A

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic phosphopeptide derived from human TRH1 around the phosphorylation site of Ser360.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

Dulbecco's PBS, pH 7.4

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to widely express in the thyrotroph cells of the anterior pituitary.

仅用于科研。不用于诊断过程。未经明确授权不得转售。