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Invitrogen
Phospho-TrkA (Tyr496)/Phospho-TrkB (Tyr515) Monoclonal Antibody (C35G9)
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Phospho-TrkA (Tyr496)/Phospho-TrkB (Tyr515) Antibody (A16663) in WB
Western blot analysis of extracts from NIH/3T3 cells stably transfected with either TrkA or TrkB, left untreated or treated with NGF or BDNF, respectively, using TrkA/TrkB (pY490/pY516) Monoclonal Antibody (top) and pooled TrkA/TrkB antibodies (bottom).
产品信息
A16663
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
C35G9
抗原
synthetic phosphopeptide corresponding to residues surrounding Tyr490 of human TrkA.
偶联物
形式
Liquid
保存条件
-20°C
运输条件
Wet ice
靶标信息
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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