A suggested positive control for Western blot is HepG2 cells.
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
蛋白别名: Butyrate response factor 1; early response factor Berg36; EGF-response factor 1; ERF-1; mRNA decay activator protein ZFP36L1; TPA-induced sequence 11b; ZFP36 ring finger protein-like 1; ZFP36-like 1; zinc finger protein 36, C3H type-like 1; Zinc finger protein 36, C3H1 type-like 1; zinc finger protein, C3H type, 36-like 1
基因别名: AW742437; AW743212; BERG36; BRF1; cMG1; D530020L18Rik; ERF-1; ERF1; RNF162B; TIS11B; ZFP36L1
分子生物学功能: RNA metabolism protein