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Positive Samples: HeLa, C6; Cellular Location: Nucleus
Immunogen sequence: LASPE
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activator protein 1; AH119; AP1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; enhancer-binding protein AP1; immediate early; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; JUND; p39; Proto-oncogene c-Jun; transcription factor AP-1; Transcription factor AP-1 subunit Jun; Transcription factor Jun; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
基因别名: AP-1; AP1; c-Jun; JUN; Junc; Rjg-9
UniProt ID: (Human) P05412, (Rat) P17325, (Mouse) P05627
Entrez Gene ID: (Human) 3725, (Rat) 24516, (Mouse) 16476