Phospho-c-Rel (Ser492, 460) Polyclonal Antibody detects endogenous levels of c-Rel only when phosphorylated at Ser492, 460.
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA., RELB (604758), NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain, ' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (Belguise and Sonenshein, 2007).
蛋白别名: BCD541; C-Rel protein; gemin 1; gemin-1; oncogene REL, avian reticuloendotheliosis; Proto-oncogene c-Rel; SMA; SMA1; SMA2; SMA3; SMA4; SMN; SMN2; SMNT; v-rel avian reticuloendotheliosis viral oncogene homolog
基因别名: C-Rel; REL
UniProt ID: (Human) Q04864
Entrez Gene ID: (Human) 5966
分子生物学功能: Rel homology transcription factor