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产品信息
PA5-64620
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human elF2b epsilon (Phospho-Ser540) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2663221 |
产品详细信息
Phospho-eIF2b epsilon (Ser540) Polyclonal Antibody detects endogenous levels of eIF2b epsilon only when phosphorylated at Ser540.
靶标信息
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eIF-2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; Translation initiation factor eIF-2B subunit epsilon
基因别名: CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM
UniProt ID: (Human) Q13144
Entrez Gene ID: (Human) 8893
分子生物学功能:
translation initiation factor
ovarian follicle development
translational initiation
aging
response to heat
response to glucose
astrocyte development
oligodendrocyte development
negative regulation of translational initiation in response to stress
response to endoplasmic reticulum stress
cellular response to drug
myelination
response to peptide hormone
positive regulation of GTPase activity
positive regulation of translational initiation
astrocyte differentiation
