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Progen
Plakoglobin Monoclonal Antibody (PG 5.1)
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产品信息
690005S
产品规格
种属反应
Bovine,
Dog,
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
PG 5.1
抗原
Plakoglobin, "band 5" protein from bovine snout epidermis
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.5% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gama-catenin; Gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; Junction plakoglobin a; OTTHUMP00000164735; Plakoglobin; Plakoglobin-1a
基因别名: ARVD12; cb80; CTNNG; D930025P04Rik; danPG; DP3; DPIII; fb11b06; JUP; jupa; PDGB; PG; PKGB; wu:fb11b06
UniProt ID: (Bovine) Q8SPJ1, (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257, (Zebrafish) Q9PVF7
Entrez Gene ID: (Bovine) 445543, (Dog) 480522, (Human) 3728, (Rat) 81679, (Mouse) 16480, (Zebrafish) 30415
structural molecule activity
protein binding
protein homodimerization activity
transcription coactivator activity
signal transducer activity
structural constituent of cell wall
protein kinase binding
protein phosphatase binding
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion
nuclear hormone receptor binding
positive regulation of cell-matrix adhesion
desmosome assembly
cell migration
regulation of cell proliferation
positive regulation of protein import into nucleus
negative regulation of blood vessel endothelial cell migration
skin development
positive regulation of angiogenesis
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
endothelial cell-cell adhesion
cellular response to indole-3-methanol
protein localization to plasma membrane
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
regulation of ventricular cardiac muscle cell action potential
atrioventricular valve morphogenesis
negative regulation of Wnt signaling pathway involved in heart development
cell adhesion
heart development
negative regulation of Wnt signaling pathway
positive regulation of transcription from RNA polymerase II promoter
cytoskeletal anchoring at plasma membrane
signal transduction
single organismal cell-cell adhesion
adherens junction organization
adherens junction assembly
protein heterooligomerization
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of cell fate specification
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
regulation of nucleic acid-templated transcription
