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Invitrogen
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Positive Control: mouse brain, rat brain
Predicted reactivity: Mouse (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Plex 1; plexin 1; plexin A1; plexin-1; Plexin-A1
基因别名: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; PlexA1; Plxn1; Plxna1; RGD1560871
UniProt ID: (Mouse) P70206
Entrez Gene ID: (Rat) 362398, (Mouse) 18844