Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals. Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
蛋白别名: DKFZp547O146; leukemia/lymphoma related factor; Leukemia/lymphoma-related factor; MGC99631; Osteoclast-derived zinc finger protein; POK erythroid myeloid ontogenic factor; POZ and Krueppel erythroid myeloid ontogenic factor; zi; Zinc finger and BTB domain-containing protein 7A
基因别名: 9030619K07Rik; 9130006G12Rik; AI452336; FBI-1; Lrf; OCZF; Pokemon; Zbtb7; Zbtb7a