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Invitrogen
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PA1-31028 detects Profilin 1 from rat, Mouse, Marsupial, human, porcine samples.
PA1-31028 has been successfully used in Western blot applications.
The PA1-31028 immunogen is: Porcine and human platelet profilin affinity purified on the antigen.
Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。