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Invitrogen
Protein APC Polyclonal Antibody
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产品信息
PA1-28190
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptidecorresponding to the Human C terminal region.
偶联物
形式
Liquid
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-28190 detects APC from rat, human, mouse samples.
PA1-28190 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-28190 immunogen is: Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).
靶标信息
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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