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Invitrogen
QKI-6 Recombinant Mouse Monoclonal Antibody (PSH10-23)
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QKI-6 Antibody (MA570047) in IHC (P)
Immunohistochemistry analysis of QKI-6 in paraffin-embedded mouse cerebellum tissue. Samples were incubated with QKI-6 monoclonal antibody (Product # MA570047) using a dilution of 1:2,000 for 1 hour at room temperature. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed... View More
产品信息
MA570047
应用
建议稀释比
已发表文章
产品规格
种属反应
Cynomolgus monkey,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH10-23
抗原
Synthetic peptide within human QKI-6 aa 281-319.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: Mouse cerebellum tissue lysate, Rat cerebellum tissue lysate.
Subcellular location: Cytoplasm, cytosol, Nucleus.
靶标信息
QKI-6 is an isoform of the RNA-binding protein QKI (Quaking), which plays a crucial role in the regulation of RNA splicing, stability, and translation. This protein is particularly important for the development and maintenance of the nervous system, including the formation and maintenance of myelin sheaths around nerve fibers. Dysregulation or mutations in QKI-6 have been associated with various neurological disorders, such as schizophrenia and demyelinating diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KH domain-containing RNA-binding protein QKI; lethal, Chr 17, U Wisconsin 1; MqkI; Protein quaking; protein quaking-like; QKI, KH domain containing, RNA binding; QKI-5 protein
基因别名: 1110003F05Rik; 1500005P18; l(17)-1Wis; l17Wis1; Qk; Qk1; QkI
UniProt ID: (Mouse) Q9QYS9
Entrez Gene ID: (Cynomolgus monkey) 102126515, (Mouse) 19317, (Rat) 100910212
vasculogenesis
mRNA processing
regulation of translation
transport
multicellular organism development
spermatid development
axon ensheathment
RNA splicing
positive regulation of gene expression
cell differentiation
myelination
muscle cell differentiation
long-chain fatty acid biosynthetic process
mRNA transport
3'-UTR-mediated mRNA destabilization
