Invitrogen

RAB11A/RAB11B Polyclonal Antibody

RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)

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RAB11A/RAB11B Antibody (PA5-120704) in ICC/IF

Immunofluorescence analysis of RAB11A/RAB11B in NIH/3T3 cells. Samples were incubated with RAB11A/RAB11B Polyclonal antibody (Product # PA5-120704) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

RAB11A/RAB11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RAB11A/RAB11B Antibody in Western Blot (WB)

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产品信息

PA5-120704

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB11A/RAB11B (NP_0046541)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.507 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2914276

产品详细信息

Positive test controls include: A-549, Mouse brain, Mouse heart, Rat liver, Rat heart.

Immunogen sequence: MGTRDDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT RSIQVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE

靶标信息

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 24KG; GTP-binding protein YPT3; RAB 11A, member oncogene family; Rab-11; RAB11B, member of RAS oncogene family; RAS oncogene family protein; Ras-related protein Rab-11A; Ras-related protein Rab-11B; YL8

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基因别名: A730055L17Rik; H-YPT3; RAB11; RAB11A; RAB11B; YL8; YPT3