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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • RAB11A/RAB11B Antibodies

          Invitrogen

          RAB11A/RAB11B Polyclonal Antibody

          查看其他2个RAB11A/RAB11B抗体
          说明书
          实验方案
          问题与答案
          技术支持
          说明书
          实验方案
          问题与答案
          技术支持

          Cite RAB11A/RAB11B Polyclonal Antibody

          • 抗体检测数据 (11)
          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 11

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          RAB11A/RAB11B Antibody (PA5-120704) in ICC/IF

          Immunofluorescence analysis of RAB11A/RAB11B in NIH/3T3 cells. Samples were incubated with RAB11A/RAB11B Polyclonal antibody (Product # PA5-120704) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          查看产品

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          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          RAB11A/RAB11B Antibody in Immunocytochemistry (ICC/IF)
          RAB11A/RAB11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAB11A/RAB11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAB11A/RAB11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAB11A/RAB11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAB11A/RAB11B Antibody in Western Blot (WB)
          RAB11A/RAB11B Antibody in Western Blot (WB)

          产品信息

          PA5-120704

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:1,000
          -

          免疫组化(石蜡) (IHC (P))

          1:50-1:200
          -

          免疫细胞化学 (ICC/IF)

          1:50-1:200
          -

          酶联免疫吸附实验 (ELISA)

          1 µg/mL
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB11A/RAB11B (NP_0046541)
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1.507 mg/mL

          纯化类型

          Affinity Chromatography

          保存液

          PBS, pH 7.3, with 50% glycerol

          内含物

          0.01% thimerosal

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2914276

          产品详细信息

          Positive test controls include: A-549, Mouse brain, Mouse heart, Rat liver, Rat heart.

          Immunogen sequence: MGTRDDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT RSIQVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE

          靶标信息

          Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: 24KG; GTP-binding protein YPT3; RAB 11A, member oncogene family; Rab-11; RAB11B, member of RAS oncogene family; RAS oncogene family protein; Ras-related protein Rab-11A; Ras-related protein Rab-11B; YL8

          查看更多 收起

          基因别名: A730055L17Rik; H-YPT3; RAB11; RAB11A; RAB11B; YL8; YPT3

          查看更多 收起

          UniProt ID: (Human) P62491, (Human) Q15907, (Rat) P62494, (Mouse) P62492, (Rat) O35509, (Mouse) P46638

          查看更多 收起

          Entrez Gene ID: (Human) 8766, (Human) 9230, (Rat) 81830, (Mouse) 53869, (Rat) 79434, (Mouse) 19326

          查看更多 收起

          功能
          GTPase activity protein binding GTP binding microtubule binding syntaxin binding myosin V binding GDP binding cadherin binding involved in cell-cell adhesion nucleotide binding
          参与通路
          intracellular protein transport exocytosis mitotic metaphase plate congression metabolic process positive regulation of epithelial cell migration regulation of multivesicular body size positive regulation of G2/M transition of mitotic cell cycle vesicle-mediated transport astral microtubule organization neuron projection development melanosome transport Rab protein signal transduction multivesicular body assembly positive regulation of axon extension regulation of long-term neuronal synaptic plasticity regulation of protein transport establishment of vesicle localization regulation of vesicle-mediated transport establishment of protein localization to organelle protein localization to plasma membrane establishment of protein localization to membrane mitotic spindle assembly exosomal secretion receptor recycling small GTPase mediated signal transduction transferrin transport insulin secretion involved in cellular response to glucose stimulus regulation of anion transport constitutive secretory pathway regulated exocytosis cellular response to acidic pH cell-cell adhesion retrograde transport, endosome to plasma membrane regulation of protein localization to cell surface regulation of endocytic recycling endocytosis cytokinesis renal water homeostasis protein transport plasma membrane to endosome transport transport cell cycle
          It has to be done as per old AB suggested Products section.
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          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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