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Invitrogen
RAB11FIP1 Polyclonal Antibody
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产品信息
PA5-30892
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human RAB11FIP1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HepG2, HCT116.
Predicted reactivity: Mouse (88%), Rat (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein. Rab11-FIP1, by interacting with Rab GTPases, is involved in the endosomal recycling process and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis. Localized to the recycling endosome, the cytoplasmic membrane and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing. As the most highly expressed isoform, isoform two of Rab11-FIP1 is expressed in brain, lung, testis, small intestine, spleen and heart. Isoform two of Rab11-FIP1 also has been found to form a homooligomer and is believed to interact with many Rab GTPases, including Rab 4A, Rab 11A, Rab 11B and Rab 25.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CBBM; CBP; hCG_41347; Rab effector protein; Rab-coupling protein; Rab-interacting recycling protein; RAB11 coupling protein; RAB11 family interacting protein 1 (class I); Rab11 family-interacting protein 1; Rab11-FIP1
基因别名: NOEL1A; rab11-FIP1; RAB11FIP1; RCP
UniProt ID: (Human) Q6AZK4
Entrez Gene ID: (Human) 80223
