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Invitrogen
RAB17 Polyclonal Antibody
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RAB17 Antibody (PA5-121144) in WB
Western blot analysis of RAB17 in extracts of various cell lines. Samples were incubated with RAB17 Polyclonal antibody (Product # PA5-121144) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-121144
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human RAB17 (NP_071894.1).
偶联物
形式
Liquid
浓度
1.37 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: A375, HepG2, 22Rv1, SW480. The target is usually found in the following locations: Cell projection, Cytoplasmic side, Lipid-anchor, Recycling endosome membrane, dendrite.
Immunogen sequence: MAQAHRTPQP RAAPSQPRVF KLVLLGSGSV GKSSLALRYV KNDFKSILPT VGCAFFTKVV DVGATSLKLE IWDTAGQEKY HSVCHLYFRG ANAALLVYDI TRKDSFLKAQ QWLKDLEEEL HPGEVLVMLV GNKTDLSQER EVTFQEGKEF ADSQKLLFME TSAKLNHQVS EVFNTVAQEL LQRSDEEGQA LRGDAAVALN KGPARQAKCC AH
靶标信息
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ras-related protein Rab-17
基因别名: AW413472; RAB17; RGD1562478
UniProt ID: (Human) Q9H0T7, (Mouse) P35292
Entrez Gene ID: (Human) 64284, (Mouse) 19329, (Rat) 503269
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
transport
intracellular protein transport
endocytosis
small GTPase mediated signal transduction
metabolic process
protein transport
regulation of endocytosis
establishment of melanosome localization
melanosome transport
endocytic recycling
Rab protein signal transduction
cilium assembly
transcytosis
filopodium assembly
regulation of dendrite development
regulation of filopodium assembly
regulation of synapse assembly
