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Immunogen sequence: MDEDVLTTLK ILIIGESGVG KSSLLLRFTD DTFDPELAAT IGVDFKVKTI SVDGNKAKLA IWDTAGQERF RTLTPSYYRG AQGVILVYDV TRRDTFVKLD NWLNELETYC TRNDIVNMLV GNKIDKENRE VDRNEGLKFA RKHSMLFIEA SAKTCDGVQC AFEELVEKII QTPGLWESEN QNKGVKLSHR EEGQGGGACG GYCSVL; Positive Samples: SH-SY5Y, A375, 293T, MCF7, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasmic side, Lipid-anchor
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GTP-binding protein Rab18; RAB18 small GTPase; Ras-related protein Rab-18
基因别名: AA959686; RAB18; RAB18LI1; WARBM3
UniProt ID: (Human) Q9NP72, (Mouse) P35293, (Rat) Q5EB77
Entrez Gene ID: (Human) 22931, (Mouse) 19330, (Rat) 307039
