Proteintech

RAB3GAP1 Monoclonal Antibody (4A3A1)

Name: RAB3GAP1 Monoclonal Antibody (4A3A1)
Brand: Proteintech
SKU: 66688-1-IG

查看其他8个RAB3GAP1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)

RAB3GAP1 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 6

RAB3GAP1 Antibody (66688-1-IG) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using RAB3GAP1 antibody (Product # 66688-1-IG, Clone: 4A3A1 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

RAB3GAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Immunogen image

Immunogen Image RAB3GAP1 Monoclonal Antibody (4A3A1)

产品信息

66688-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

免疫组化（石蜡） (IHC (P))

1:500-1:2,000

免疫细胞化学 (ICC/IF)

1:400

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

4A3A1

抗原

RAB3GAP1 Fusion Protein Ag17710 (502-851 aa encoded by BC146809)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: PGDAGKAGD QLVPDNLKET DKEKGEVGKS WDSWSDSEEE FFECLSDTEE LKGNGQESGK KGGPKEMANL RPEGRLYQHG KLTLLHNGEP LYIPVTQEPA PMTEDLLEEQ SEVLAKLGTS AEGAHLRARM QSACLLSDME SFKAANPGCS LEDFVRWYSP RDYIEEEVID EKGNVVLKGE LSARMKIPSN MWVEAWETAK PIPARRQRRL FDDTREAEKV LHYLAIQKPA DLARHLLPCV IHAAVLKVKE EESLENISSV KKIIKQIISH SSKVLHFPNP EDKKLEEIIH QITNVEALIA RARSLKAKFG TEKCEQEEEK EDLERFVSCL LEQPEVLVTG AGRGHAGRII H (502-851 aa encoded by BC146809)

靶标信息

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Rab 3 GAP p130; Rab3 GAP p130; RAB3 GTPase activating protein subunit 1 (catalytic); RAB3 GTPase-activating protein 130 kDa subunit; Rab3 GTPase-activating protein catalytic subunit; Rab3-GAP; Rab3-GAP p130

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基因别名: 1700003B17Rik; 4732493F09Rik; AL117896; KIAA0066; P130; RAB3GAP; RAB3GAP1; RAB3GAP130; WARBM1

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UniProt ID: (Human) Q15042, (Mouse) Q80UJ7

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Entrez Gene ID: (Human) 22930, (Mouse) 226407

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功能

guanyl-nucleotide exchange factor activity GTPase activator activity Rab guanyl-nucleotide exchange factor activity Rab GTPase binding GTPase-activating protein

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