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Invitrogen
RAB3a Polyclonal Antibody
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RAB3a Antibody (PA1-4691) in WB
Western blot was performed using RAB3A Recombinant Polyclonal Antibody (Product # PA1-4691) and a 27 kDa band corresponding to RAB3A was observed in Mouse brain, Mouse cerebellum, Rat brain and Rat cerebellum but not in Mouse skeletal muscle, Mouse liver, Rat skeletal muscle and Rat liver. Tissue extract (30 µg lysate) of Mouse brain (Lane 1), Mouse cerebellum (Lane 2), Mouse skeletal muscle (Lane 3), Mouse liver (Lane 4), Rat brain (Lane 5), Rat cerebellum (Lane 6), Rat skeletal muscle (Lane 7) and Rat liver (Lane 8) were electrophoresed ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-4691
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the N-terminal region of rat RAB3A conjugated to KLH
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
25 µg
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with human, mouse, Xenopus and non-human primate based on 100% sequence homology.
In Western blot, this antibody is specific for ~27 kDa Rab 3 protein.
靶标信息
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C18A3.6; Ras-related protein Rab-3A; Ras-related small GTP binding protein 3A
基因别名: RAB3; RAB3A
UniProt ID: (Rat) P63012, (Mouse) P63011
Entrez Gene ID: (Rat) 25531, (Mouse) 19339
respiratory system process
intracellular protein transport
vesicle docking involved in exocytosis
mitochondrion organization
neuromuscular synaptic transmission
axonogenesis
metabolic process
protein secretion
post-embryonic development
synaptic vesicle exocytosis
synaptic vesicle maturation
regulation of exocytosis
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
Rab protein signal transduction
positive regulation of ATPase activity
synaptic vesicle recycling
regulation of short-term neuronal synaptic plasticity
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
protein localization to plasma membrane
positive regulation of regulated secretory pathway
transport
exocytosis
small GTPase mediated signal transduction
protein transport
synaptic vesicle transport
evoked neurotransmitter secretion
regulation of long-term synaptic potentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
