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Proteintech
RABEPK/p40 Polyclonal Antibody
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产品信息
15105-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RABEPK/p40 Fusion Protein Ag2593 (1-372 aa encoded by BC065725)
偶联物
形式
Liquid
浓度
0.18 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKQLPVLEP GDKPRKATWY TLTVPGDSPC ARVGHSCSYL PPVGNAKRGK VFIVGGANPN GSFSDVHTMD LGKHQWDLDT CKGLLPRYEH ASFIPSCTPD RIWVFGGANQ SGNRNCLQVL NPETRTWTTP EVTSPPPSPR TFHTSSAAIG NQLYVFGGGE RGAQPVQDTK LHVFDANTLT WSQPETLGNP PSPRHGHVMV AAGTKLFIHG GLAGDRFYDD LHCIDISDMK WQKLNPTGAA PAGCAAHSAV AMGKHVYIFG GMTPAGALDT MYQYHTEEQH WTLLKFDTLL PPGRLDHSMC IIPWPVTCAS EKEDSNSLTL NHEAEKEDSA DKVMSHSGDS HEESQTATLL CLVFGGMNTE GEIYDDCIVT VVD (1-372 aa encoded by BC065725)
靶标信息
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 40 kDa Rab9 effector protein; p40; Rab9 effector p40; Rab9 effector protein with kelch motifs
基因别名: bA65N13.1; p40; RAB9P40; RABEPK
UniProt ID: (Human) Q7Z6M1
Entrez Gene ID: (Human) 10244
