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Invitrogen
RAD17 Polyclonal Antibody
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产品信息
PA1-4131
产品规格
种属反应
Yeast
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues S(10) T K R S L K K K K I R K I(23) of the 75 kDa S. pombe RAD17.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-4131 detects yeast RAD17.
PA1-4131 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~75 kDa protein representing RAD17 in yeast.
The PA1- 4131 immunogen is a synthetic peptide corresponding to residues S(10) T K R S L K K K K I R K I(23) of the 75 kDa S. pombe RAD17.
靶标信息
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; RAD17 (Ser647); Rad17 like protein
基因别名: RAD17; YOR368W
UniProt ID: (Baker's yeast) P48581
Entrez Gene ID: (Baker's yeast) 854550
