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Invitrogen
RAD21 Monoclonal Antibody (1B6D1)
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图: 1 / 8
RAD21 Antibody (MA5-31884) in ICC/IF
Immunocytochemistry analysis of RAD21 in Hela cells (green). Sample was incubated with RAD21 monoclonal antibody (Product # MA5-31884) using a dilution of 1:200-1:1000 followed by DRAQ5 fluorescent DNA dye (blue), and Alexa Fluor- 555 phalloidin (red labeled actin filaments) .
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-31884
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1B6D1
抗原
Purified recombinant fragment of human RAD21 (AA: 287-403) expressed in E. coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-31884 has been tested in indirect ELISA.
靶标信息
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: FLJ25655; FLJ40596; h NXP-1; HR21spA; KIAA0078; KIAA0078RAD21; kleisin; nuclear matrix protein 1; NXP-1; protein involved in DNA double-strand break repair; RAD21 homolog; SCC1 homolog; sister chromatid cohesion 1; unnamed protein product
基因别名: CDLS4; hHR21; HR21; HRAD21; MCD1; MGS; NXP1; SCC1
UniProt ID: (Human) O60216
Entrez Gene ID: (Human) 5885, (Rat) 314949
response to hypoxia
regulation of transcription from RNA polymerase II promoter
sister chromatid cohesion
positive regulation of gene expression
negative regulation of gene expression
negative regulation of G2/M transition of mitotic cell cycle
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-10 production
negative regulation of glial cell apoptotic process
negative regulation of neuron apoptotic process
negative regulation of mitotic metaphase/anaphase transition
positive regulation of sister chromatid cohesion
protein localization to chromatin
chromatin looping
replication-born double-strand break repair via sister chromatid exchange
double-strand break repair
DNA recombination
reciprocal meiotic recombination
establishment of mitotic sister chromatid cohesion
establishment of meiotic sister chromatid cohesion
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
