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Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
BLAST analysis indicates 100 % homology of the immunizing sequence with RAD54 from human. Cross reactivity with RAD54 protein homologues from other sources may not occur as sequence homology varies by at least one amino acid residue in this sequence.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATR2; DNA repair and recombination protein RAD54-like; h hRAD54; hHR54; MGC2094; MRXHF1; RAD54 homolog; RP5-875J14.1; SFM1; SHS; XH2; XNP; ZNF-HX
基因别名: hHR54; HR54; hRAD54; RAD54A; RAD54L
UniProt ID: (Human) Q92698
Entrez Gene ID: (Human) 8438