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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 76%, Rat- 76%.
Sequence of this protein is as follows: KEQEEKSDSL VKYFSVVWCK PSKKKHKKWE GDAVLIVKGK SFILKNLEGK DIGRGIGYKF KELEKIEEGQ TLMICGKEIE VMGVISPDDF SSGRCFQLGG GSTAISHSSQ VARKCFSNP
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA repair and recombination protein RAD54B; RAD54 homolog B
基因别名: RAD54B
Entrez Gene ID: (Human) 25788