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Invitrogen
RAD9 Monoclonal Antibody (6B5)
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产品信息
MA5-32968
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
6B5
抗原
Recombinant full length Human RAD9A.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
RAD9 is a component of the 9-1-1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesions upon damage by the RAD17-replication factor C clamp loader complex. RAD9 acts as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell cycle checkpoint control protein RAD9A; DNA repair exonuclease rad9 homolog A; hRAD9; mRAD9; RAD9 homolog A; RAD9 homolog A (S. pombe); Rad9-like protein; rCG47324-like
基因别名: RAD9; RAD9A
UniProt ID: (Human) Q99638, (Mouse) Q9Z0F6
Entrez Gene ID: (Human) 5883, (Mouse) 19367, (Rat) 100361529
DNA replication checkpoint
DNA damage checkpoint
DNA replication
DNA repair
cellular response to DNA damage stimulus
intra-S DNA damage checkpoint
cellular response to ionizing radiation
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
cell cycle checkpoint
response to radiation
