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Invitrogen
RAE1 alpha/beta/delta/epsilon Monoclonal Antibody (199205)
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产品信息
MA5-61040
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
199205
抗原
BaF3 mouse pro-B cell line transfected with Rae-1 beta (Accession # NP_033043) and Mouse myeloma cell line NS0-derived recombinant mouse Rae-1 delta Leu29-Ser227 (Accession # Q9JI58)
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
RAE1 (RNA Export 1) is a gene that plays a pivotal role in the nuclear export of mRNA in eukaryotic cells. This gene encodes a protein that is integral to the mRNA export machinery, ensuring the proper transport of mRNA from the nucleus to the cytoplasm for translation. The gene has several isoforms, including RAE1 alpha, beta, delta, and epsilon, which may have unique or overlapping functions in different tissues or developmental stages. The proper functioning of RAE1 and its isoforms is crucial for maintaining normal cellular processes and gene expression. Disruptions or mutations in the RAE1 gene can lead to significant defects in mRNA export, potentially causing a range of diseases, including neurodevelopmental disorders and cancers. Ongoing research into RAE1 and its various isoforms is essential for a deeper understanding of mRNA transport mechanisms and their broader implications in cellular health and disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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