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Invitrogen
RALBP1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-144683
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PPDVVSDDEK DHGKKKGKFK KKEKRTEGYA AFQEDSSGDE AESPSKMKRS KGIHVFKKPS FSKKKEKDFK IKEKPKEEKH KEEKHKEEKH KEKKSKDLTA ADVVKQWKEK KKKKKPIQEP EVPQIDVPNL KP
Antigen sequence identity: Mouse 95%; Rat 95%
靶标信息
Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 76 kDa Ral-interacting protein; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; ral-interacting protein 1; RIP; unnamed protein product
基因别名: RIP1; RLIP1; RLIP76
UniProt ID: (Human) Q15311
Entrez Gene ID: (Human) 10928
positive regulation of protein phosphorylation
receptor-mediated endocytosis
chemotaxis
signal transduction
small GTPase mediated signal transduction
regulation of Cdc42 protein signal transduction
regulation of GTPase activity
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
transmembrane transport
positive regulation of mitochondrial fission
doxorubicin transport
drug transmembrane export
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
