Invitrogen

RAMP1 (extracellular) Polyclonal Antibody

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RAMP1 (extracellular) Antibody in Western Blot (WB) — Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and rat pancreas (lanes 3 and 6) with RAMP1 (extracellular) polyclonal antibody (Product # PA5-77720) using a dilution of 1:400 (brain) and 1:200 (pancreas).

RAMP1 (extracellular) Antibody — CRDPDYGTLIQE, corresponding to amino acid residues 27-38 of rat RAMP1

产品信息

PA5-77720

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:200-1:400	-
免疫细胞化学 (ICC/IF)	1:50	-

产品规格
种属反应	Mouse, Rat
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Peptide CRDPDYGTLIQE, corresponding to amino acid residues 27-38 of rat RAMP1
偶联物	Unconjugated
形式	Lyophilized
浓度	0.85 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 1% BSA
内含物	0.05% sodium azide
保存条件	-20°C
RRID	AB_2736495

产品详细信息

Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.

Reconstitute using 50 uL deionized water.

靶标信息

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

仅用于科研。不用于诊断过程。未经明确授权不得转售。