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Proteintech
RANK/TNFRSF11A Polyclonal Antibody
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产品信息
32528-1-AP
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein
偶联物
形式
Liquid
浓度
400 µg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: VTLPCTQERH YEHLGRCCSR CEPGKYLSSK CTPTSDSVCL PCGPDEYLDT WNEEDKCLLH KVCDAGKALV AVDPGNHTAP RRCACTAGYH WNADCECCRR NTECAPGFGA QHPLQLNVDT VCTPCLLGFF SDVFSSTDKC KPWTNCTVLG KMEAHQGTTE SDVVCSSSLT LIKPPKEAQ
靶标信息
RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD265; ODFR; Osteoclast differentiation factor receptor; receptor activator of NF-kappaB; Receptor activator of NF-KB; Tumor necrosis factor receptor superfamily member 11A
基因别名: Ly109; mRANK; ODFR; OFE; RANK; RGD1563614; Tnfrsf11a; TRANCE-R
UniProt ID: (Mouse) O35305
Entrez Gene ID: (Mouse) 21934, (Rat) 498206
ossification
adaptive immune response
multicellular organism development
programmed cell death
osteoclast differentiation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to cytokine
response to tumor necrosis factor
positive regulation of JUN kinase activity
lymph node development
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
circadian temperature homeostasis
mammary gland alveolus development
response to interleukin-1
positive regulation of fever generation by positive regulation of prostaglandin secretion
TNFSF11-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
response to radiation
