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Invitrogen
RAP1B Polyclonal Antibody
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产品信息
PA5-88865
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human Rap1B (NP_0564611)
偶联物
形式
Liquid
浓度
1.33 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDAQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTDDVP MILVGNKCDL EDERVVGKEQ GQNLARQWNN CAFLESSAKS KINVNEIFYD LVRQINRKTP VPGKARKKSS CQLL; Positive Samples: A-549, HeLa, Mouse kidney; Cellular Location: Cell junction, Cell membrane, Cytoplasm, cytosol
靶标信息
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GTP-binding protein smg p21B; Ras family small GTP binding protein RAP1B; Ras-related protein Rap-1b; RAS-related protein RAP1B; small GTP binding protein
基因别名: 2810443E11Rik; K-REV; OK/SW-cl.11; RAL1B; RAP1B
UniProt ID: (Human) B4DW74, (Mouse) Q99JI6
Entrez Gene ID: (Human) 5908, (Mouse) 215449
microvillus assembly
Rap protein signal transduction
establishment of endothelial barrier
cellular response to cAMP
regulation of cell junction assembly
regulation of establishment of cell polarity
signal transduction
small GTPase mediated signal transduction
metabolic process
cell proliferation
negative regulation of calcium ion-dependent exocytosis
positive regulation of ERK1 and ERK2 cascade
negative regulation of synaptic vesicle exocytosis
