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产品信息
PA5-50740
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to a region derived from internal residues of human RAS p21 protein activator 2 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
3 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636192 |
产品详细信息
The antibody detects endogenous levels of total RASA2 protein.
靶标信息
The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CM-AVM; CMAVM; DKFZp434N071; GAP1m; GTPase-activating protein 1m; GTPase-activating protein of RAS; p120RASGAP; PKWS; Ras GTPase-activating protein 2; RASA
基因别名: GAP1M; RASA2; RASGAP
UniProt ID: (Human) Q15283
Entrez Gene ID: (Human) 5922
分子生物学功能:
GTPase-activating protein
