Search Thermo Fisher Scientific
图: 1 / 2
Antibody detects endogenous levels of total RBM5.
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein G15; Putative tumor suppressor LUCA15; Renal carcinoma antigen NY-REN-9; RNA-binding motif protein 5; RNA-binding protein 5
基因别名: D030069N10Rik; G15; H37; LUCA15; RBM5; RMB5
UniProt ID: (Human) P52756, (Mouse) Q91YE7
Entrez Gene ID: (Human) 10181, (Mouse) 83486