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产品信息
H00023543-M02
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
5E11
抗原
RBM9 (AAH13115, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEKKKMVTQG NQEPTTTPDA MVQPFTTIPF PPPPQNGIPT EYGVPHTQDY AGQTGEHNLT LYGSTQAHGE QSSNSPSTQN GSLTTEGGAQ TDGQQSQTQS
靶标信息
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fox-1 homolog B; Fox-1 homolog Fxh; fox-1 homologue; Fyn-binding molecule 2; Hexaribonucleotide-binding protein 2; Repressor of tamoxifen transcriptional activity; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA-binding motif protein 9; RNA-binding protein 9
基因别名: dJ106I20.3; Fbm2; Fox-2; FOX2; Fxh; HNRBP2; HRNBP2; RBFOX2; RBM9; RTA
UniProt ID: (Human) O43251, (Mouse) Q8BP71
Entrez Gene ID: (Human) 23543, (Mouse) 93686
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
nervous system development
RNA splicing
fibroblast growth factor receptor signaling pathway
regulation of definitive erythrocyte differentiation
RNA metabolic process
radial glia guided migration of Purkinje cell
intracellular estrogen receptor signaling pathway
regulation of cell proliferation
negative regulation of transcription, DNA-templated
dendrite morphogenesis
neuromuscular process controlling balance
regulation of RNA splicing
