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Invitrogen
RCA60 Monoclonal Antibody (CP75)
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产品信息
MA1-91115
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CP75
抗原
Natural RCA60, full length.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.7 mg/mL
规格
500 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
MA1-91115 detects Ricinus communis agglutinin 60 from various samples.
靶标信息
Ricinus communis agglutinin 60 is a heterodimeric glycoprotein consisting of an A chain (RTA, ricin toxin A chain) disulphide-linked to a B chain (RTB, ricin toxin B chain). RTA is an N glycosidase, responsible for ricin cytotoxicity, that depurinates adenine residue 4324 of the 28S rRNA, thus inactivating protein synthesis. Since its endocytotic properties are very limited, RTA alone shows a very low level of cytotoxicity. RTB is a galactose specific lectin containing three galactose-binding sites. Mutation or deletion of any one of these sites reduces the ability of ricin to penetrate into the cell.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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