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Invitrogen
RCC1 Polyclonal Antibody
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产品信息
PA1-5868
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
His-tagged recombinant Xenopus RCC1 protein purified from E. coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-5868 detects RanGEF in human and xenopus samples.
PA1-5868 has been successfully used in immunofluorescence, immunoprecipitation, immunohistochistry and Western blot procedures.
The PA1-5868 immunogen is His-tagged recombinant Xenopus RCC1 protein purified from E. coli.
靶标信息
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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