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Abnova
RCC1 Monoclonal Antibody (1C1)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00001104-M02
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C1
抗原
RCC1 (AAH07300, 312 a.a. approximately 421 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: EGKAYSLGRA EYGRLGLGEG AEEKSIPTLI SRLPAVSSVA CGASVGYAVT KDGRVFAWGM GTNYQLGTGQ DEDAWSPVEM MGKQLENRVV LSVSSGGQHT VLLVKDKEQS
靶标信息
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell cycle regulatory protein; CHC1; guanine nucleotide-releasing protein; RAN guanine nucleotide exchange factor; unnamed protein product
基因别名: CHC1; IIAAN; RCC1-I
UniProt ID: (Human) P18754
Entrez Gene ID: (Human) 1104
G1/S transition of mitotic cell cycle
mitotic spindle organization
chromosome segregation
mitotic nuclear envelope reassembly
regulation of mitotic nuclear division
regulation of mitotic cell cycle
viral process
spindle assembly
positive regulation of cell cycle process
regulation of mitotic spindle assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
