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Proteintech
REC8 Polyclonal Antibody
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产品信息
10793-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
REC8 Fusion Protein Ag1250 (188-548 aa encoded by BC010887)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human REC8. This antibody can recognize the monomeric, non-phosphorylated form (63-70 kDa) of REC8 and other forms(80-100 kDa) which represent either post translationally modified forms or alternative transcript products.
Immunogen sequence: VLPPEAITI LEAEPIRMLE IEGERELPEV SRRELDLLIA EEEEAILLEI PRLPPPAPAE VEGIGEALGP EELRLTGWEP GALLMEVTPP EELRLPAPPS PERRPPVPPP PRRRRRRRLL FWDKETQISP EKFQEQLQTR AHCWECPMVQ PPERTIRGPA ELFRTPTLSG WLPPELLGLW THCAQPPPKA LRRELPEEAA AEEERRKIEV PSEIEVPREA LEPSVPLMVS LEISLEAAEE EKSRISLIPP EERWAWPEVE APEAPALPVV PELPEVPMEM PLVLPPELEL LSLEAVHRAV ALELQANREP DFSSLVSPLS PRRMAARVFY LLLVLSAQQI LHVKQEKPYG RLLIQPGPRF H (188-548 aa encoded by BC010887)
靶标信息
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cohesin Rec8p; cohesion rec8p; human homolog of rad21, S. pombe; kleisin-alpha; meiotic cohesion Rec8; meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family; Meiotic recombination protein REC8 homolog; meiotic recombination protein REC8-like 1; REC8 homolog; REC8-like 1; recombination and sister chromatid cohesion protein homolog
基因别名: HR21spB; Mei8; mrec; REC8; REC8L1; Rec8p
UniProt ID: (Human) O95072, (Mouse) Q8C5S7
Entrez Gene ID: (Human) 9985, (Mouse) 56739
double-strand break repair via homologous recombination
oocyte maturation
sister chromatid cohesion
meiotic nuclear division
synaptonemal complex assembly
reciprocal meiotic recombination
male meiosis I
spermatogenesis
spermatid development
fertilization
seminiferous tubule development
chromosome segregation
synapsis
meiotic cell cycle
