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Invitrogen
REC8 Polyclonal Antibody
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REC8 Antibody (PA5-120322) in WB
Western blot analysis of REC8 in extracts of Rat testis. Samples were incubated with REC8 Polyclonal antibody (Product # PA5-120322) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-120322
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 194-561 of mouse REC8 (NP_064386.2).
偶联物
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: Rat testis. The target is usually found in the following locations: Chromosome, Nucleus.
Immunogen sequence: EVITLQEAEP IRMLQIEGEQ DLPEISRGDL ELLIAEKDDA ILLEERQRGR LLRQRRASLP LDESREEPRA LEGAGLVSAL SPPAPAQVEG IQEALPGQVF PPEVQKMTGW EPGALLTEVT PPQELRLPAP PSTEKRLPSL QRPLPRRHRR RQLLFWDKET QISREKFEEQ LQTGAHCWEY PVAQPPKRML TSPAELFRTP TLSGWLPPEL LGLWTHCAQV PQRMLRQRPQ LETEETVEEE RAADEEERRK TEALSEIEVL REAQEPSGPL MLSSELSLEA AEDEKSRTSL IPPEWWAWSE EGQPEPPALP MLPELPEVPM EMPPRPELSS EAVLRAVALK LQANKELDFS SLVPPLSPRK LASRVFYL
靶标信息
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cohesin Rec8p; meiosis specific sister chromatid cohesion protein; Meiotic recombination protein REC8 homolog; REC8 homolog; rec8 {ECO:0000250|UniProtKB:Q8C5S7}; REC8-like 1
基因别名: Rec8; Rec8L1
UniProt ID: (Rat) Q6AYJ4
Entrez Gene ID: (Rat) 290227
