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Bethyl Laboratories
REDD1 Polyclonal Antibody
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REDD1 Antibody (A302-169A) in ICC/IF
Detection of human REDD1 by immunocytochemistry. Sample: NBF-fixed asynchronous, Cobalt-treated HeLa cells. Antibody: Affinity purified rabbit anti-REDD1 (Product # A302-169A) (lot 1) used at a dilution of 1:500 (2 µg/mL). Detection: Red-fluorescent goat anti-rabbit IgG H&L cross-adsorbed Antibody DyLight®594 used at a dilution of 1:100.
产品信息
A302-169A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 and 50 of Human protein regulated in development and DNA damage response 1 (DNA-damage-inducible transcript 4).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For ICC, formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Panda, Orangutan, Monkey, Gorilla and Chimpanzee
靶标信息
DDIT4 gene ontology annotations related to this gene include cellular response to dexamethasone stimulus; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of glycolytic process; negative regulation of TOR signaling; protein-containing complex disassembly; reactive oxygen species metabolic process; response to hypoxia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4; HIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD-1; RP11-442H21.1
基因别名: DDIT4; Dig2; REDD-1; REDD1; RTP801
UniProt ID: (Human) Q9NX09
Entrez Gene ID: (Human) 54541
response to hypoxia
neuron migration
brain development
cell proliferation
negative regulation of peptidyl-threonine phosphorylation
neuron differentiation
negative regulation of TOR signaling
negative regulation of peptidyl-serine phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
protein complex disassembly
negative regulation of glycolytic process
neurotrophin TRK receptor signaling pathway
defense response to virus
reactive oxygen species metabolic process
positive regulation of neuron death
negative regulation of intracellular signal transduction
