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OriGene
REN Monoclonal Antibody (OTI1A10), TrueMAB™
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产品信息
CF807126
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1A10
抗原
Human recombinant protein fragment corresponding to amino acids 131-406 of human REN produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: angiotensin-forming enzyme; Angiotensinogenase; EC 3.4.23; EC 3.4.23.15; FLJ10761; Renin; renin precursor, renal
基因别名: HNFJ2; REN
UniProt ID: (Human) P00797
Entrez Gene ID: (Human) 5972
kidney development
mesonephros development
angiotensin maturation
renin-angiotensin regulation of aldosterone production
proteolysis
regulation of blood pressure
male gonad development
hormone-mediated signaling pathway
protein catabolic process
response to lipopolysaccharide
cellular response to drug
response to immobilization stress
drinking behavior
regulation of MAPK cascade
cell maturation
beta-amyloid metabolic process
response to cAMP
response to cGMP
