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Immunogen sequence: YPLPEGLPPT LQPEYLQAAF PKPKWDCQLF DSYSESLPAN QQPRDLNRME KTSVKDMADL PVPNQDVTSD DKQALKSTIN EALPKDVSED PATPKDSNSL KARPRSRSYS STSIEEAMKR GEDPPTPPPR PQKTHSRASS LDLN
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 83%.
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: partner of Ral-binding protein 1; Partner of RalBP1; RalBP1-associated Eps domain-containing protein 2; RALBP1-interacting protein 2
基因别名: POB1; REPS2
UniProt ID: (Human) Q8NFH8
Entrez Gene ID: (Human) 9185