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Abnova
RFP2 Monoclonal Antibody (2A11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010206-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, lambda
分类
Monoclonal
类型
Antibody
克隆号
2A11
抗原
RFP2 (NP_005789, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MELLEEDLTC PICCSLFDDP RVLPCSHNFC KKCLEGILEG SVRNSLWRPA PFKCPTCRKE TSATGINSLQ VNYSLKGIVE KYNKIKISPK MPVCKGHLGQ
靶标信息
The protein encoded by the RFP2 gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. The gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell chronic lymphocytic leukemia tumor suppressor Leu5; CLL-associated RING finger; leukemia-associated protein 5; putative E3 ubiquitin-protein ligase; RFP2; putative tumor suppressor; putative transcription factor; putative tumor suppressor RFP2; RBBC protein; RBCC protein; ret finger protein 2; RING finger protein 77; RING-type E3 ubiquitin transferase TRIM13; tripartite motif protein 13; tripartite motif-containing protein 13; unnamed protein product
基因别名: CAR; DLEU5; LEU5; RFP2; RNF77
UniProt ID: (Human) O60858
Entrez Gene ID: (Human) 10206
positive regulation of macroautophagy
protein ubiquitination
ERAD pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation by host of viral release from host cell
innate immune response
positive regulation of transcription, DNA-templated
protein autoubiquitination
antiviral innate immune response
endoplasmic reticulum mannose trimming
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