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Proteintech
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Immunogen sequence: ETKIDVSYE YRFLEFTTLS AAELPGSSAV RLASLRDLPA QLLELYQQGF SLAALHPFVQ PTHEREKTPL EHIFRAILIK KTDRSQKTDL HNEGYILELD CCSSLDHPTD QKLIPEFIKK IQEAASQGLK FVGVIPQYHS SVNSAGSSAP VSTANSTEDA RDAKNARGDH ASLENEKPGT GDVCSAPAGR NQSPEPSSGP RGEVPLAKQP SSPSGEGDGG ELSPQGVSKT LDGPESNPLE VHEEPLSGKM EIFTLFNKPK SHQKCRQYYP VTIPLHVSKN GQTVSGLDAN WLEHMSDHFR KGGMLVNAVF YLGIVNDSLH GLTDGVFIFE AVSTEDSKTI QGYDAIV (29-374 aa encoded by BC100667)
Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), cell migration-inducing gene 2 protein, PIB10, PIG9 or MIG2, is a 578 amino acid cell membrane protein and lipid anchor that is essential for raft cell assembly and maintenance. A member of the raftlin family, Raftlin modulates B-cell antigen receptor-mediated signaling, TCR signals, and is involved in T cell-mediated immune responses. The gene encoding Raftlin maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell migration-inducing gene 2 protein; proliferation-inducing protein 10; proliferation-inducing protein 9; Raft-linking protein; Raftlin
基因别名: KIAA0084; MIG2; PIB10; PIG9; RAFTLIN; RFTN1
UniProt ID: (Human) Q14699
Entrez Gene ID: (Human) 23180