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OriGene
RFX3 Monoclonal Antibody (OTI3F7), TrueMAB™
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RFX3 Antibody (CF505916) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RFX3 (RC201137, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RFX3. Positive lysates LY403344 (100 µg) and LC403344 (20 µg) can be purchased separately from OriGene.
产品信息
CF505916
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI3F7
抗原
Full length human recombinant protein of human RFX3 produced in HEK293T cell.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bA32F11.1; DNA binding protein RFX3; Regulatory factor X 3; regulatory factor X, 3 (influences HLA class II expression); Transcription factor RFX3
基因别名: RFX3
UniProt ID: (Human) P48380
Entrez Gene ID: (Human) 5991
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription regulatory region DNA binding
winged helix/forkhead transcription factor
type B pancreatic cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
endocrine pancreas development
cilium assembly
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
regulation of insulin secretion
cilium-dependent cell motility
epithelial cilium movement involved in determination of left/right asymmetry
type B pancreatic cell maturation
positive regulation of type B pancreatic cell development
