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Invitrogen
RGS10 Polyclonal Antibody
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产品信息
PA5-46819
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human RGS10
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: DQIFNLMKYD SYSRFLKSDL FLKHKRTEEE EEDLPDAQTA AKRASRIYNT
Sequence homology: Cow: 81%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 90%; Rat: 90%
靶标信息
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Regulator of G-protein signaling 10; regulator of G-protein signalling 10; RGS10
基因别名: 2310010N19Rik; RGS10
UniProt ID: (Human) O43665, (Mouse) Q9CQE5
Entrez Gene ID: (Human) 6001, (Mouse) 67865
